At issue: a default analysis for schizophrenia research

The concept that there are at least three clinical syndromes within schizophrenia has been influential, and the significance of these syndromes is supported by a growing number of studies. However, the meaning of these syndromes is not clear. The yield of research studies could be increased by the application of a "default" data analysis, in which the differential association--if any--of the three syndromes with the dependent variable(s) of a study is determined.