亚低温治疗对心肺复苏后脑复苏的影响

目的 探讨亚低温治疗对心脏骤停后脑复苏的治疗效果.方法 选取2007年5月至2011年4月兰州市第一人民医院急诊科收治的心脏骤停成功复苏的患者37例,完全随机分为常规治疗组(18例)与亚低温治疗组(19例),比较2组患者自主循环恢复后24、48、72 h急性生理和慢性健康状况评分Ⅱ(A-PACHEⅡ)与格拉斯哥昏迷评分(GCS).结果 亚低温组自主呼吸恢复时间[(7.1±3.2)h比(12.7±3.0)h]与意识恢复时间[(13.1±3.2)h比(17.4±3.1)]明显短于常规治疗组(P＜0.05).72 h时亚低温治疗组APACHEⅡ评分低于常规治疗组,差异有统计学意义[(16.86±7.71)比(22.20±10.73),P＜0.05].48 h时GCS评分比较差异有统计学意义[(9.52±2.11)比(3.67±1.04),P＜0.05].结论 亚低温治疗有促进心肺复苏自主循环恢复患者脑功能恢复的作用.

Effect of moderate hypothermia treatment in patlents with cerebral recovery after cardiopulmonarv resusci tation

Objective To study effect of moderate hypothernia treatment in patients with cerebral resuscitation after cardiac arrest survivors.Methods A total of 37 patients of successful cardiopulmonary resuscitation were randomly divided into the hypothermia therapy group( n = 19)and the routine therapy group( n = 18 ),Acute physiology and Chronic Health Evaluation Ⅱ (APACHE Ⅱ )and Glasgow Coma Scale(GCS) of patients at 24 hours,48 hours,72 hours were compared between hypothermia therapy group and routine therapy group respectively.Results The recovery time of autonomous respiratory and consciousness in the bypothermua therapy group was shorter than those in routne therapy group.There was a significantly difference of APACHE Ⅱ score at 72 hour in two groups,P ＜0.05.There was a significantly difference in GCS score on 48 hour,in two groups,P ＜ 0.05.Conclusion Moderate hypothermia can promote the restoration of cerebral function in the patients with successful cardiopulmonary(CPR).