磁共振成像评估舌鳞状细胞癌浸润深度的准确性分析

目的以光镜下病理切片为参照,分析磁共振成像(magnetic resonance imaging,MRI)测量的舌鳞状细胞癌浸润深度的准确性,为临床提供参考。方法选取2018年1月至2020年9月就诊于山西医科大学第一医院口腔科和中南大学湘雅口腔医院的73例舌鳞状细胞癌患者,术前均行MRI评估舌鳞状细胞癌浸润深度,术中冰冻病理切片再次测量舌鳞状细胞癌浸润深度。结果T1加权成像测量的舌鳞状细胞癌浸润深度较病理结果平均高估1.11 mm(95%CI=0.51~1.70,t=3.72,P<0.001),相关系数r为0.95;T2加权像平均高估2.17 mm(95%CI=1.32~3.02,t=5.10,P<0.001),相关系数r为0.92。Bland?Altman图显示T1、T2加权像与病理测量的浸润深度一致性佳。结论MRI测量的舌鳞状细胞癌浸润深度较为准确,与病理测量结果相比有平均1~2 mm的高估,其中T1加权像优于T2加权像。

Accuracy analysis of MRI in the depth of invasion assessment of tongue squamous cell carcinoma

Objective To analyze the accuracy of the infiltrating depth of tongue squamous cell carcinoma measured by magnetic resonance imaging(MRI)using pathological sections under a light microscope to provide a clinical reference.Methods Seventy?three patients with tongue squamous cell carcinoma who visited the Department of Stomatology of the First Hospital of Shanxi Medical University and Xiangya Stomatological Hospital from January 2018 to September 2020 were selected.Preoperative MRI was performed to evaluate the infiltration depth of tongue squamous cell carcinoma,and intraoperative frozen pathological sections were used to confirm the infiltration depth of tongue squamous cell carcinoma measurement.Results The infiltration depth of tongue squamous cell carcinoma measured by T1?weighted imaging was 1.11 mm(95%CI=0.51-1.70;t=3.72;P<0.001),and the correlation coefficient r was 0.95.The T2?weighted average overestimation was 2.17 mm(95%CI=1.32?3.02;t=5.10;P<0.001),and the correlation coefficient was 0.92.The Bland?Altman plot showed good consistency between T1?and T2?weighted images and patho?logic measurements.Conclusion The infiltration depth of tongue squamous cell carcinoma measured by MRI is more accurate,with an average overestimation of 1-2 mm compared with pathological measurements,and T1?weighted images are better than T2?weighted images.