经子宫动脉MTX灌注及栓塞联合清宫治疗剖宫产后瘢痕处妊娠的效果分析

目的 分析经子宫动脉甲氨蝶呤(MTX)灌注及栓塞联合清宫治疗剖宫产后瘢痕处妊娠的效果.方法 95例剖宫产后瘢痕处妊娠患者,按照治疗方法不同分为联合组(50例)与对照组(45例).对照组选择米非司酮与MTX治疗后实施清宫术,联合组予以经子宫动脉MTX灌注及栓塞联合清宫治疗.比较两组临床指标,术前及术后1、2周血β-人绒毛...

Effect analysis of uterine artery MTX perfusion and embolization combined with uterine evacuation in the treatment of cesarean scar pregnancy

Objective To analyze the effect of uterine artery methotrexate(MTX)perfusion and embolization combined with uterine evacuation in the treatment of cesarean scar pregnancy.Methods A total of 95 patients with cesarean scar pregnancy were divided into combined group(50 cases)and control group(45 cases).The control group was treated with mifepristone and MTX before uterine evacuation,and the combined group was treated with uterine artery perfusion and embolization combined with uterine evacuation.The clinical indicators,bloodβ-human chorionic gonadotropin(β-HCG)levels before operation,1 and 2 weeks after operation,and the incidence of adverse reactions were compared between the two groups.Results The operative blood loss of the combined group was less than that of the control group,and hospitalization time,bloodβ-HCG level recovery time,menstrual recovery time,and lesion disappearance time of the combined group were shorter than those of the control group,and the difference was statistically significant(P<0.05).1 and 2 weeks after operation,the levels ofβ-HCG of the two groups were decreased compared with that before operation,and the combined group were(4123.15±727.28)and(1032.33±263.26)mIU/ml,which were lower than(5637.83±1014.57)and(1827.75±654.19)mIU/ml of the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions 8.00%of the combined group was lower than 31.11%of the control group,and the difference was statistically significant(P<0.05).Conclusion Uterine artery MTX perfusion and embolization combined with uterine evacuation is safe and targeted in the treatment of scar pregnancy after cesarean section.The two treatment methods can play a synergistic role in promoting the early remission of patients’condition and lowering the risk of disease.