静脉给予右美托咪定与丙泊酚用于蛛网膜下腔麻醉中度镇静的临床效果比较

目的 对蛛网膜下腔麻醉患者静脉给予右美托咪定与丙泊酚进行中度镇静的临床效果进行比较.方法 100例蛛网膜下腔麻醉患者,按照随机数字表法分为研究组和对照组,每组50例.研究组给予右美托咪定进行中度镇静,对照组患者给予丙泊酚进行中度镇静.比较两组患者麻醉指标、不良反应发生情况及麻醉满意度.结果 研究组患者有效麻醉时间为(2...

Comparison of clinical effects of intravenous administration of dexmedetomidine and propofol for moderate sedation in subarachnoid anesthesia

Objective To compare the clinical effect of intravenous administration of dexmedetomidine and propofol for moderate sedation in subarachnoid anesthesia.Methods A total of 100 patients with subarachnoid anesthesia were divided into research group and control group according to random numerical table,with 50 cases in each group.The research group received dexmedetomidine for moderate sedation,and the control group received propofol for moderate sedation.The anesthesia indexes,occurrence of adverse reactions and anesthesia satisfaction were compared between the two groups.Results The effective anesthesia time(226.12±5.73)min and time required for observers assessment of alertness/sedation scale(OAA/S)score to recover to≥4 points(27.31±2.29)min of the research group were longer than(143.27±4.35)and(15.36±1.23)min,and the difference was statistically significant(P<0.05).The incidence of adverse reactions of the research group was 18.0%,which was lower than 36.0%of the control group,and the difference was statistically significant(P<0.05).The anesthesia satisfaction of the research group was 78.0%,which was higher than 36.0%of the control group,and the difference was statistically significant(P<0.05).Conclusion Intravenous administration of dexmedetomidine shows better effect than propofol for moderate sedation in subarachnoid anesthesia,which can not only effectively improve the various indicators of the patient,but also significantly improve the satisfaction of patients after surgery,which is worthy of scientific research and clinical promotion.