伊马替尼治疗不同时期慢性粒细胞白血病的疗效对比

目的 研究伊马替尼治疗不同时期慢性粒细胞白血病(CML)的临床疗效.方法 选取28例早期慢性粒细胞白血病患者作为观察组,另选取28例晚期慢性粒细胞白血病患者作为参照组.两组均采用伊马替尼治疗,观察比较两组患者的治疗效果及不良反应发生率.结果 观察组患者治疗总有效率96.43％ 高于参照组的75.00％,差异具有统计学意...

Efficacy of imatinib in the treatment of chronic myeloid leukemia at different stages

Objective To study the clinical efficacy of imatinib in the treatment of chronic myeloid leukemia(CML)at different stages.Methods There were 28 patients with early chronic myeloid leukemia selected as the observation group,and 28 patients with advanced chronic myeloid leukemia as the reference group.Both groups were treated with imatinib,and the therapeutic effect and incidence of adverse reactions of the two groups were observed and compared.Results The total effective rate of treatment 96.43%of the observation group was higher than 75.00%of the reference group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions 3.57%of the observation group was obviously lower than 25.00%of the reference group,and the difference was statistically significant(P<0.05).Conclusion Imatinib can obviously improve the therapeutic effect of patients with early chronic myeloid leukemia with lower incidence of adverse reactions and high safety.