| 慢性前列腺炎患者前列腺液16S rDNA检测的临床意义 |
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| 引用本文： | 刘士军,陈国强,叶海云,王晓峰. 慢性前列腺炎患者前列腺液16S rDNA检测的临床意义[J]. 中华男科学杂志, 2006, 12(5): 413-415 |
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| 作者姓名： | 刘士军 陈国强 叶海云 王晓峰 |
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| 作者单位： | 北京大学人民医院泌尿外科,北京,100044 |
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| 摘 要： | 目的:探讨慢性前列腺炎患者前列腺液16S rDNA检测的临床意义。方法:对116例慢性前列腺炎患者前列腺液采用PCR方法检测其16S rDNA,比较不同亚型前列腺炎的16S rDNA阳性率并分析其相关性。结果:29例Ⅱ型前列腺炎前列腺液16S rDNA PCR均阳性,阳性率100%;87例Ⅲ型前列腺炎前列腺液16S rDNA PCR阳性71例,阳性率82%,其中ⅢA型前列腺炎前列腺液PCR阳性率94%(45/48),ⅢB型前列腺炎前列腺液PCR阳性率67%(26/39)。结论:16S rDNA的检测可能成为慢性前列腺炎分型的一个指标。
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| 关 键 词： | 慢性前列腺炎 16SrDNA 前列腺液 |
| 文章编号： | 1009-3591（2006）05-0413-03 |
| 收稿时间： | 2005-07-06 |
| 修稿时间： | 2005-12-05 |
Detection and Significance of 16S rDNA in the Prostatic Secretions of Patients with Chronic Prostatitis |
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| LIU Shi-jun,CHEN Guo-qiang,YE Hai-yun,WANG Xiao-feng. Detection and Significance of 16S rDNA in the Prostatic Secretions of Patients with Chronic Prostatitis[J]. National journal of andrology, 2006, 12(5): 413-415 |
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| Authors: | LIU Shi-jun CHEN Guo-qiang YE Hai-yun WANG Xiao-feng |
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| Affiliation: | Department of Urology, People's Hospital of Peking University, Beijing 100044, China. liushijun1206@sina.com |
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| Abstract: | OBJECTIVE: To evaluate the expression and significance of 16S rDNA in prostatic secretions (EPS) of chronic prostatitis. METHODS: 16S rDNA was detected in EPS of 116 patients with chronic prostatitis by PCR. RESULTS: 16S rDNA were positively expressed in all 29 cases of II type chronic bacterial prostatitis and 71 out of 87 cases of III type chronic prostatitis (82%). The positive rates were 94% (45/48) and 67% (26/39) in lIIA and IIIB chronic prostatitis respectively. There was a statistical difference in 16S rDNA positive rate between IIIA and IlB chronic prostatitis (P < 0.01). CONCLUSION: Detection of 16s rDNA may be a useful index for the diagnosis and classification of chronic prostatitis. |
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| Keywords: | 16S rDNA |
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