BNP、cTnI、T3联合检测对老年心力衰竭的临床意义

目的：探讨BNP、cTnI、T3联合检测对老年心力衰竭的临床意义。方法回顾性分析2012年10月-2013年12月期间在我院住院治疗的138例老年心力衰竭患者（HF组），按照美国纽约心脏病学会（NYHA）分级标准将HF组患者的心功能分为Ⅱ级60例，Ⅲ-Ⅳ级78例。对照组70例，均为与HF组患者同期来我院进行健康体检的健康研究对象。对患者BNP、cTnI、T3进行单独检测及联合检测。结果 NYHA Ⅱ级、NYHAⅢ-Ⅳ级治疗前的BNP、cTnI水平均高于对照组，T3水平低于对照组；NYHAⅢ-Ⅳ级治疗前的BNP、cTnI水平均高于NYHA Ⅱ级， T3水平低于NYHAⅡ级；NYHAⅢ-Ⅳ级治疗后的BNP、cTnI水平与治疗前比较出现降低，T3水平出现升高，差异有统计学意义（P＜0.05）。BNP＋cTnI＋T3检测敏感性高于BNP、cTnI、T3单独检测，差异有统计学意义（P＜0.05）。结论 BNP、cTnI、T3联合检测有较高的敏感性，对早期诊断HF有重要的意义。

Clinical significance of BNP,cTnI,T3 combined detection in elderly heart failure

Objective To investigate the clinical significance of BNP, cTnI, T3 combined detection in elderly heart failure. Methods A total of 138 cases of elderly patients with heart failure （HF group） selected from October 2012 to December 2013 in our hospital were retrospectⅣe analyzed, according to the New York Heart Association （NYHA） classification standards will HF cardiac function of patients 60 cases of class Ⅱ, Ⅲ-Ⅳ grade 78 cases. The control group was 70 cases, were selected to our hospital for physical examination of healthy subjects on the same period with HF patients. BNP, cTnI, T3 were alone tested and joint detected. Results BNP, cTnI levels of NYHA Ⅱ level, NY-HAⅢ-Ⅳ-class before treatment were higher than the control group , T3 levels were lower than the control group;BNP, cTnI levels of NYHAⅢ-Ⅳ-class before treatment were higher than NYHA Ⅱ level, T3 levels were lower than NYHA Ⅱ level; BNP NYHAⅢ-Ⅳ level after treatment, cTnI levels before treatment appeared reduce, T3 levels ap-pear higher, the difference was significant （P〈0.05）. BNP＋cTnI＋T3 detect sensitⅣe were higher than BNP, cTnI, T3 alone testing, the difference was significant（P〈0.05）. Conclusion BNP, cTnI, T3 joint detection has high sensitⅣity for early diagnosis of HF has important significance.