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Non-canonical activation of inflammatory caspases by cytosolic LPS in innate immunity
Affiliation:1. National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China;2. National Institute of Biological Sciences, Beijing 102206, China;1. Howard Hughes Medical Institute, United States;2. Department of Molecular and Cell Biology, United States;3. Cancer Research Laboratory, University of California, Berkeley, Berkeley, CA 94720, United States;1. Harvard Medical School and Division of Gastroenterology, Boston Children’s Hospital, Boston, MA 02115, USA;2. Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan 20126, Italy;3. Unit of Cell Signalling and Innate Immunity, Humanitas Clinical and Research Center, Rozzano 20089, Italy;4. Graduate Program in Molecular Microbiology, Sackler School of Biomedical Sciences, Tufts University School of Medicine, Boston, MA 02111, USA;5. Graduate Program in Immunology, Sackler School of Biomedical Sciences, Tufts University School of Medicine, Boston, MA 02111, USA;6. Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA;1. Institute for Molecular Bioscience, The University of Queensland, St Lucia 4072, Australia;2. Institut für Klinische Chemie und Pathobiochemie, Klinikum rechts der Isar, Technische Universität München, 81675 Munich, Germany;3. School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia 4072, Australia;4. Australian Infectious Disease Research Centre, The University of Queensland, St Lucia 4072, Australia;5. Department of Biochemistry, University of Lausanne, 1066 Epalinges, Switzerland;1. Department of Microbiology and Immunology, University of Western Ontario, London N6A 5C1, Canada;2. National Institute of Biological Sciences, Beijing 102206, China;3. Centre for Infection and Immunity, Queen’s University Belfast, Belfast BT9 7AE, UK;4. National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China;5. National Institute of Biological Sciences, Beijing, Collaborative Innovation Center for Cancer Medicine, Beijing 102206, China;1. Department of Neurology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, China;1. Institute of Microbiology, ETH Zürich, 8093 Zürich, Switzerland;2. Department of Biochemistry, University of Lausanne, 1066 Epalinges, Switzerland;3. Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama 230-0045, Japan
Abstract:
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