A2BC-Type Porphyrin SAM on Gold Surface for Bacteria Detection Applications: Synthesis and Surface Functionalization |
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| Authors: | Laurie Neumann,Lea Kö nemund,Valentina Rohnacher,Annemarie Pucci,Hans-Hermann Johannes,Wolfgang Kowalsky |
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| Affiliation: | 1.Labor für Elektrooptik/Institut für Hochfrequenztechnik, TU Braunschweig, Bienroder Weg 94/Schleinitzstraße 22, D-38106 Braunschweig, Germany; (L.N.); (L.K.); (W.K.);2.Kirchhoff Institute for Physics, Heidelberg University, Im Neuenheimer Feld 227, D-69120 Heidelberg, Germany; (V.R.); (A.P.) |
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| Abstract: | Currently used elaborate technologies for the detection of bacteria can be improved in regard to their time consumption, labor intensity, accuracy and reproducibility. Well-known electrical measurement methods might connect highly sensitive sensing systems with biological requirements. The development of modified sensor surfaces with self-assembled monolayers (SAMs) from functionalized porphyrin for bacteria trapping can lead to a highly sensitive sensor for bacteria detection. Different A2BC-type porphyrin structures were synthesized and examined regarding their optical behavior. We achieved the synthesis of a porphyrin for SAM formation on a gold surface as electrode material. Two possible bio linkers were attached on the opposite meso-position of the porphyrin, which allows the porphyrin to react as a linker on the surface for bacteria trapping. Different porphyrin structures were attached to a gold surface, the SAM formation and the respective coverage was investigated. |
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| Keywords: | porphyrin SAM formation modified gold surface E. coli immobilization |
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