| 傣雅解护肝方对四氯化碳致小鼠急性肝损伤的保护作斥 |
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| 引用本文： | 吕显荣,张闯,陈普,许力跃,姜宇波,陈眉,张超.傣雅解护肝方对四氯化碳致小鼠急性肝损伤的保护作斥[J].云南中医学院学报,2009(3):27-29. |
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| 作者姓名： | 吕显荣 张闯 陈普 许力跃 姜宇波 陈眉 张超 |
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| 作者单位： | 云南中医学院,云南昆明650500 |
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| 基金项目： | 云南中医学院科学研究基金资助 |
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| 摘 要： | 目的：研究傣雅解护肝方对四氯化碳（CCl4）致小鼠急性肝损伤模型的保护作用。方法：用傣雅解护肝方预防性给药7天后，用CCl4造模，检测造模后小鼠血清谷丙转氨酶（ALT）、谷草转氨酶（AST）活性；显微镜观察小鼠肝组织病理学变化。结果：傣雅解护肝方各剂量组能明显抑制CCl4致小鼠急性肝损伤模型A岍、AST的升高（P〈0．05）；减轻四氯化碳对肝脏细胞的病理损伤。结论：傣雅解护肝方对CCl4所致小鼠急性肝损伤有明显的保护作用。
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| 关 键 词： | 傣雅解护肝方 四氯化碳 急性肝损伤 |
Protective Effect of DYJHGF on Acute Liver Injury Induced by CCl4 in Mice |
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| LV Xian- rong,ZHANG Chuang,CHEN Pu,XU Li -yue,JIANG Yu- bo,CHEN Mei,ZHANG Chao.Protective Effect of DYJHGF on Acute Liver Injury Induced by CCl4 in Mice[J].Journal of Yunnan College of Traditional Chinese Medicine,2009(3):27-29. |
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| Authors: | LV Xian- rong ZHANG Chuang CHEN Pu XU Li -yue JIANG Yu- bo CHEN Mei ZHANG Chao |
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| Institution: | (Yunnan University of TCM, Kunming Yunnan 650200, China) |
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| Abstract: | Objective： To study the protective effect of DYJHGF on acute liver injury induced by CCl4 in mice. Methods： DYJHGF was administered by pouring it into stomachs of mice for seven days preventatively, and then, acute liver injury model was induced by CCl4. ALT and AST activities were measured. ResuLts： Different concentrations of the DYJHGF significantly decreased the activities of serum ALT and AST （ P 〈 0. 05 ）, and lighten the extent of degeneration and necrosis. Conclusion ： DYJHGF showed protective effects on acute liver injury induced by CCl4 in mice significantly. |
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| Keywords: | DYJHGF CCl4 Acute Liver Injury |
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