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脑梗死患者治疗前后血浆同型半胱胺酸水平变化的探讨
引用本文:刘洪爱.脑梗死患者治疗前后血浆同型半胱胺酸水平变化的探讨[J].泰山医学院学报,2009,30(11).
作者姓名:刘洪爱
作者单位:泰山疗养院检验科,山东,泰安,271000
摘    要:目的探讨脑梗死患者应用叶酸、维生素B 12治疗前后血浆同型半胱胺酸(Hcy)水平的变化及临床意义。方法检测114例脑梗死患者及99例健康对照者的Hcy、叶酸、维生素B 12水平;再将脑梗死组随机分为用药组和非用药组,用药组给予维生素B 12制剂联合叶酸治疗,治疗4周后复测血浆Hcy、叶酸和维生素B 12水平。结果脑梗死组和对照组之间血浆Hcy、叶酸和维生素B 12水平存在明显差异(P<0.01);予以补充叶酸和维生素B 12治疗后,用药组血浆Hcy水平明显下降(P<0.01)。结论Hcy增高是脑血管病中一独立危险因素;降低Hcy水平对减少脑梗死的发生率具有十分重要的临床意义。

关 键 词:脑梗死  同型半胱氨酸  叶酸  维生素B12

Study the cerebral infarction patients before and after treatment of plasma homocysteine levels of change
LIU Hong-ai.Study the cerebral infarction patients before and after treatment of plasma homocysteine levels of change[J].Journal of Taishan Medical College,2009,30(11).
Authors:LIU Hong-ai
Institution:LIU Hong-ai(Test Dept.of Taishan Sanatorium; Taian 271000; China);
Abstract:Objective: To study the cerebral infarction patients with folic acid,vitamin B 12 before and after treatment of plasma homocysteine(Hcy) levels of change and clinical significance.Method Detection of 114 patients with cerebral infarction and 99 healthy controls of the Hcy,folate,vitamin B 12 levels;then cerebral infarction group were randomly divided into treatment group and non-medication group,medication group were given vitamin B 12 folic acid preparation combined therapy,treatment for 4 weeks after the ...
Keywords:cerebral Infarction  homocysteine  folic Acid  vitamin B 12
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