Decrease in the volume of white matter lesions with improvement of hepatic encephalopathy |
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Authors: | Mínguez B Rovira A Alonso J Córdoba J |
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Affiliation: | Servicio de Medicina Interna-Hepatología, Hospital Universitario Valle Hebron, Departament de Medicina, Universitat Autònoma de Barcelona, Barcelona Spain. |
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Abstract: | MR imaging has found abnormalities compatible with low-grade edema in the brain of patients with cirrhosis that have been related to hepatic encephalopathy. We present 3 patients with hepatic encephalopathy who exhibit supratentorial focal or diffuse white matter lesions compatible with small-vessel brain disease. The volume and number of white matter lesions reduced with the improvement of hepatic encephalopathy, suggesting the participation of the blood-brain barrier in the pathogenesis of brain edema in hepatic encephalopathy. |
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