| TORCH感染介入性产前诊断195例分析 |
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| 引用本文： | 周祎,方群,陈健生,游泽山,陈筠虹. TORCH感染介入性产前诊断195例分析[J]. 广东医学, 2002, 23(8): 784-786 |
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| 作者姓名： | 周祎 方群 陈健生 游泽山 陈筠虹 |
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| 作者单位： | 中山大学附属第一医院妇产科胎儿医学中心,广州,510080 |
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| 摘 要： | 目的 探讨TORCH感染介入性产前诊断方法和检测方法，研究其宫内传播率。方法 对195例TORCH－IgM阳性孕妇在B超介导下行羊膜腔穿刺术和脐静脉穿刺术，获得的羊水和脐血用PCR（RT－PCR），ELISA和MEIA法检测TORCH－DNA（RNA）或TORCH－IgM。结果 羊膜腔穿刺术和脐静脉穿刺术全部成功，无严重并发症。其确诊胎儿宫内TORCH感染17例，宫内TORCH感染率为8．7％。结论 介入性产前诊断手术安全可靠，TORCH感染可宫内传播，TORCH感染的检测方法有待进一步改善。
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| 关 键 词： | TORCH感染 介入性产前诊断 宫内传播 羊膜腔穿刺 脐静脉穿刺 |
| 修稿时间： | 2002-06-20 |
Analysis of 195 cases of invasive prenatal diagnosis for TORCH infections |
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| Zhou Yi,Fang Qun,Chen Jiansheng,et al.. Analysis of 195 cases of invasive prenatal diagnosis for TORCH infections[J]. Guangdong Medical Journal, 2002, 23(8): 784-786 |
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| Authors: | Zhou Yi Fang Qun Chen Jiansheng et al. |
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| Affiliation: | Zhou Yi,Fang Qun,Chen Jiansheng,et al. Fetal Medicine Unit,Department of Obstetrics and Gynecology,First Affiliated Hospital,Sun Yat-sen University Guangzhou,510080 |
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| Abstract: | Objective To investigate the invasive prenatal diagnosis and detecting methods for TORCH infections and to study the in utero transmittion rate. Methods Amniocentesis and cordocentesis by guided B-ultrasound were performed on 195 cases of pregnant women with positive TORCH-IgM. TORCH-DNA(RNA) or TORCH-IgM from amniotic fluid and cord blood samples was detected by PCR(RT-PCR), ELISA or MEIA. Results All the performances of amniocentesis and cordocentesis were successful without severe maternal and fetuses' complications. 17 fetuses were infected with an infection rate 8 7% in utero transmittion. Conclusion Invasive prenatal diagnosis is safe and efficient. TORCH infections can transmit in utero. Detecting methods for TORCH infections need to be improved. |
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| Keywords: | TORCH infection Invasive prenatal diagnosis In utero transmit Examine |
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