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男性2型糖尿病患者血浆性激素水平对胰岛素敏感性的影响
引用本文:汪红玲,张建明,朱俊.男性2型糖尿病患者血浆性激素水平对胰岛素敏感性的影响[J].皖南医学院学报,2007,26(3):204-205.
作者姓名:汪红玲  张建明  朱俊
作者单位:马鞍山市中心医院,内分泌科,安徽,马鞍山,243000
摘    要:目的:探讨男性2型糖尿病患者血浆性激素对胰岛素敏感性的影响。方法:对37例男性2型糖尿病患者测定血清空腹血糖、空腹胰岛素水平,计算胰岛素敏感指数ISI=In(FPG×FINS)-1],同时测定血清睾酮(T)、雌二醇(E2)水平,并计算E2/T,分析血清性激素与胰岛素敏感指数的相关性,34例非糖尿病人作为对照组。结果:血浆睾酮水平与胰岛素敏感性呈正相关(r=0.264,P<0.05)。结论:2型糖尿病患者低血浆性激素水平促进胰岛素抵抗的发生。

关 键 词:糖尿病  睾酮  雌二醇  胰岛素敏感性
文章编号:1002-0217(2007)03-0204-02
修稿时间:2007-02-23

Effect of serum sex hormone levels on insulin sensitivity in men with type 2 diabetes
WANG Hong-ling,ZHANG Jian-ming,ZHU Jun.Effect of serum sex hormone levels on insulin sensitivity in men with type 2 diabetes[J].Acta Academiae Medicinae Wannan,2007,26(3):204-205.
Authors:WANG Hong-ling  ZHANG Jian-ming  ZHU Jun
Institution:Department of Endocrinology, Central Hospital, Maanshan 243000
Abstract:Objective: To examine the relationship between serum testosterone levels and insulin sensitivity in men.Methods:A total of 37 men with type 2 diabetes were determined fasting plasma glucose(FPG)、fasting insulin(FINS).Insulin sensitivity was calculated by ISI=In(FPG×FINS)-1.The serum testosterone and estradiol was assayed and calculated E2 /T.Results:Serum testosterone levels positive correlated with ISI(r=0.264,P<0.05).Conclusion:Low serum sex hormone levels in men with type 2 diabetes may promote insulin resistance in men.
Keywords:diabetes  testosterone  estradiol  insulin sensitivity
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