Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution |
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| Authors: | Heller Frank Florian Peter Bojarski Christian Richter Jan Christ Melanie Hillenbrand Bernd Mankertz Joachim Gitter Alfred H Bürgel Nataly Fromm Michael Zeitz Martin Fuss Ivan Strober Warren Schulzke Jörg D |
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| Affiliation: | Department of Gastroenterology, Charité, Campus Benjamin Franklin, Berlin, Germany. |
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| Abstract: | |
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| Keywords: | EGTA, ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid FACS, fluorescence-activator cell sorting IFN, interferon IL, interleukin LDH, lactate dehydrogenase LPMC, lamina propria mononuclear cell NF-κB, nuclear factor κB NKT cell, natural killer T cell PCR, polymerase chain reaction P-STAT-6, phosphorylated STAT-6 Rt, transepithelial electrical resistance TNF, tumor necrosis factor TUNEL, terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling |
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