孕妇缺碘对婴儿智能的影响

报道了孕妇碘缺乏病（ＩＤＤ）于妊娠早期补碘成不补碘对其所生婴儿智能发育的影响。根据尿碘、血清促甲状腺激素（ＴＳＨ）值、Ｔ４值、甲状腺肿等指标诊断，缺碘孕妇于初孕１～４个月补碘一次（碘油丸含碘４００ｍｇ／丸为Ｃ组），另设缺碘不补碘组（Ｂ组）和正常对照组（Ａ组）。跟踪孕妇，产后每月测婴儿身长、体重、智能（采用ＣＤＣＣ测试法）。结果证明补碘孕妇所生婴儿的身长、体重、智能均高于缺碘对照组（Ｐ＜０．０１或０．０５），并发现母亲缺碘其婴儿智力发育明显迟缓。孕妇缺碘如能早期补碘可预防新生儿的智力发育不良。

Effect of iodine deficiency on pregnant women and mental development of their infants

This investigation studied the effect of iodine deficiency on pregnant women. Iodine supplement at the begining of pregnancy can correct the delayed intelligence.Iodine deficiency was diagnosed by urine iodine,serum TSH, T4, and goitered status,etc. Iodine deficient women were administered iodine once in the first 4 monthof pregnancy,I 400mg /capsule (group C). Groups B and A are iodine deficient pregnant women with placebo and normal control women. Each group included 50 women. In the following 12-15 months the infant's height, body weight and circumference of head were measured. about 6 months, all infants were examined for body weight, height and intelligence including MDI and PDI (mental development index and psychomotor development index). Group B infant body weight, height and MDI and PDI were lower than group C, and group C infant growth and intelligence were better than group B. There were no significant deferences between group A and C. It proved that iodine deficient pregnant women must get enough iodine in early pregnancy.