碰撞池-电感耦合等离子体质谱法测定血液透析水中的10种元素

目的建立碰撞池-电感耦合等离子体质谱测定血液透析水中铍、铬、铜、砷、镉、锑、钡、汞、铊、铅的检测方法。方法以45Sc、89Y、103Rh、175Lu作为内标元素,应用电感耦合等离子体质谱直接测定血液透析水中铍、铬、铜、砷、镉、锑、钡、汞、铊、铅等10种元素的含量。结果 10种元素在0.0～50.0μg/L范围内线性关系良好,相关系数为0.999 5～1.000 0,各元素的检出限为0.002～0.069μg/L,定量下限为0.007～0.230μg/L,相对标准偏差（RSD）为0.57%～10.76%,加标回收率为85.0%～106.9%。结论该法灵敏度高、精密度好,结果准确可靠,适合测定血液透析水中10种金属和非金属元素。

Determination of elements in hemodialysis water by inductively coupled plasma mass spectrometry with ORS

Objective To establish a method for determination of Be, Cr, Cu, As, Cd, Sb, Ba, Hg, T1, and Pb in hemodialysis water by inductively coupled plasma mass spectrometry （ICP-MS） with octopole reaction system （ORS） for practical requirement. Methods Contents of Be, Cr, Cu, As, Cd, Sb, Ba, Hg, T1, and Pb in samples of hemodialysis water were determined by ICP-MS, using 45Sc, S9y, 103 Rh, and 175 Lu as the internal standard elements. Results Linear relationships of the ten elements were optimal in the range of 0.0 - 50.0 μg/L. The correlation coefficients were 0. 999 5 - 1. 000 0, the limits of detection were between 0. 002 -0. 069 μg/L, the determination limits were 0. 007 -0. 230μg/L, the rela- tive standard deviation were 0. 57% - 10. 76% , and the spike recoveries were 85. 0% - 106. 9%. Conclusion The method was quick and accurate to determine Be, Cr, Cu, As, Cd, Sb, Ba, Hg, T1, and Pb in hemodialysis water by ICP-MS with ORS.