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放射活性~(103)Pd粒子近距离照射治疗肿瘤初步研究
引用本文:陈萍,魏献忠,梁伟坚,刘衍民,吴开俊,孙北望,曾可伟,梁健新,陈汉章. 放射活性~(103)Pd粒子近距离照射治疗肿瘤初步研究[J]. 现代临床医学生物工程学杂志, 2001, 0(6)
作者姓名:陈萍  魏献忠  梁伟坚  刘衍民  吴开俊  孙北望  曾可伟  梁健新  陈汉章
基金项目:广州市科技局立项资助 .计划编号 :(JB0 2 ) 2 0 0 1 - 2 - 0 36 - 0 1 - 3
摘    要:目的 研究放射活性10 3钯 ( 10 3Pd)粒子近距离照射各种肿瘤的治疗效果及应用价值 .方法  31例确诊为恶性肿瘤患者通过不同方式植入10 3Pd粒子 ,观察肿瘤大小变化、局部复发和远处转移情况 ;并按RTOG/EORTC急性或后期放疗副作用评分标准进行评分 .结果 近期疗效观察理想 ,副作用小 ,安全可行 .RTOG/EORTC评分 0分有 2 8/31例 .2 /31例死亡患者在行此治疗前均已经发生远处转移 ,最后死于重要脏器衰竭 .结论 10 3Pd粒子适用于对射线低至中性敏感的肿瘤永久性植入治疗

关 键 词:肿瘤治疗  近距离治疗  103Pd粒子

Preliminary Study of Permanent ~(103)Pd Radioactive Seed Implantation on Maligmant Tumor in Brachytherapy
CHEN Ping,WEI Xian zhong,LIANG Wei jian,et al.. Preliminary Study of Permanent ~(103)Pd Radioactive Seed Implantation on Maligmant Tumor in Brachytherapy[J]. Journal of Modern Clinical Medical Bioengineering, 2001, 0(6)
Authors:CHEN Ping  WEI Xian zhong  LIANG Wei jian  et al.
Abstract:Objective To assess the brachytherapy effectiveness and the utilization of 103 Pd seeds in tumor therapy. Methods 31 103 Pd seed brachytherapy patients were studied in RTOG/EORTC acute and late radiation morbidity scoring criteria. Results The brachytherapy effect of 103 Pd seeds in tumor patients is obvious.28 of 31 patients showed 0 score in acute criteria. 2 of 31 patients died without the brachytherapy reason. The late scoring is still needed. Conclusions The 103 Pd seeds can be safely used in brachytherapy of tumors which are low or midiam sensitive to radiotherapy.
Keywords:Tumor therapy  Brachytherapy  103 Pd seeds
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