| n-HA/PA66复合生物活性融合器在颈椎病前路减压融合术中的初步应用研究 |
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| 引用本文： | 欧云生,蒋电明,权正学,安洪,唐可,李佳,沈昌焕. n-HA/PA66复合生物活性融合器在颈椎病前路减压融合术中的初步应用研究[J]. 生物医学工程学杂志, 2010, 0(2) |
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| 作者姓名： | 欧云生 蒋电明 权正学 安洪 唐可 李佳 沈昌焕 |
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| 作者单位： | 重庆医科大学附属第一医院骨科; |
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| 基金项目： | 国家高新技术研究发展(“863”)计划资助项目(2002AA326020) |
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| 摘 要： | 分析52例颈椎病行前路减压、n-HA/PA66复合生物活性融合器植骨、钛钉板系统内固定颈椎前路重建手术患者的临床资料,探讨自行研制的纳米羟基磷灰石/聚酰胺66(n-HA/PA66)复合生物活性融合器在颈椎病前路减压固定融合手术中的初步临床疗效。所有术后均获得6～25个月(平均13个月)的随访。患者术前症状均得到改善,JOA评分术前平均为10.4分,术后为15.7分。n-HA/PA66复合生物活性融合器于术后3～6个月骨性融合。颈椎生理曲度、椎间高度、颈椎稳定性均维持良好。无融合器下沉、塌陷、移位发生,无感染、内固定物松动、脱落、断裂等并发症。n-HA/PA66复合生物活性融合器能有效重建和维持颈椎体的结构和高度,可能是一种理想的颈椎植骨替代材料。
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| 关 键 词： | 纳米羟基磷灰石 聚酰胺66 椎间融合器 颈椎病 颈椎融合术 |
Preliminary Application of the Fusion Cage of Biomimetic n-HA/PA66 Composites in Anterior Cervical Intervertebral Fusion |
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| Ou Yunsheng Jiang Dianming Quan Zhengxue An Hong Tang Ke Li Jia Shen Changhuan. Preliminary Application of the Fusion Cage of Biomimetic n-HA/PA66 Composites in Anterior Cervical Intervertebral Fusion[J]. Journal of biomedical engineering, 2010, 0(2) |
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| Authors: | Ou Yunsheng Jiang Dianming Quan Zhengxue An Hong Tang Ke Li Jia Shen Changhuan |
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| Affiliation: | Ou Yunsheng Jiang Dianming Quan Zhengxue An Hong Tang Ke Li Jia Shen Changhuan (Department of Orthopaedics,the First Affiliated Hospital of Chongqing Medical Uinversity,Chongqing 400016,China) |
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| Abstract: | This study was aimed to evaluate the preliminary efficacy and the safety of the fusion cage made of biomimetic nano-hydroxyapatite and polyamide 66(n-HA/PA66) composites for the structural reconstruction and the restoration of height of vertebral body in the case of cervical spondylosis by anterior surgical procedures.52 patients with cervical spondylosis,received the therapy by discectomy with or without vertebrae resection and decompression,and the fusion cage of n-HA/PA66 vertebra implant with bone chip,... |
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| Keywords: | Nano-hydroxyapatite Polyamide 66 Intervertebral cage Cervical spondylosis Fusion |
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