瑞芬太尼与小剂量芬太尼用于小儿先心病手术快通道麻醉的对比研究

目的 对比瑞芬太尼和小剂量芬太尼用于小儿先心病手术快通道麻醉的效果.方法 对年龄2～12岁拟在体外循环下行房缺或室缺修补术患儿24例,根据阿片药物用药的不同随机分为两组,R组(n=12)为瑞芬太尼麻醉,F组(n=12)为小剂量芬太尼麻醉.分别记录两组入室(T0)、诱导(T1)、锯胸骨(T2)、缝合胸骨(T3)、手术结束...

Comparison between Remifentanil and Small Dose Fentanyl Used in Fast Track Cardiac Anesthesia for Pediatric

Objective To compare the effects of remifentanil and small dose of fentanyl in pediatric undergoing surgical repair of congenital cardiac defects.Methods Twenty-four pediatric underwent elective surgery repair of congenital cardiac defects were divided into two groups randomly.The patient were anesthetized with remifentanil(group R) or fentanyl(group F).The changes of MAP,HR were observed during anesthesia when getting into the operating room(T0),induction of anesthesia(T1),spliting the sternum(T2),suturing the sternum(T3),the surgery was finished(T4).Recorded the time of disturbe,discharge from ICU and the condition of analgesia.Results The MAP and HR in two groups were significant lower at T1、T2 than T0.The HR in group R was significant lower than those in group F at T1.The Glu of the two groups was significant increased at T3、T4 than T0,The Glu in group F was significantly higher than those in group R at T3.There was no significantly different in the time of disturbe and discharge from ICU among the two groups.The condition of analgesia in group F was better than group R.Conclusion Both remifentanil and small dose of fentanyl could be safely used in pediatric heart surgery.Remifentanil could control the stress hormone better at the beginning of CPB than fentanyl,but with more slowly HR.The small dose of fentanyl could make better analgesia.