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双黄连粉针与头孢呋辛钠粉针配伍稳定性考察
引用本文:关俊威. 双黄连粉针与头孢呋辛钠粉针配伍稳定性考察[J]. 黑龙江医药, 2011, 24(1): 92-93
作者姓名:关俊威
作者单位:哈药集团三精制药股份有限公司,150010
摘    要:目的:考察双黄连粉针和头孢呋辛钠粉针配伍稳定性.方法:采用氯化钠溶液作为溶媒,考察双黄连粉针与头孢呋辛钠粉针在室温下配伍后外观、pH值和微粒变化,并采用HPLC法考察配伍液中黄芩苷含量的变化.结果:双黄连粉针与头孢呋辛钠粉针配伍产生白色沉淀,含量下降,有白色沉淀产生,微粒数增多.结论:双黄连粉针不宜与头孢呋辛钠粉针配伍...

关 键 词:双黄连粉针  配伍  稳定性  高效液相色谱

Study on compatible stability of shuanghuanglian powder injection and cefuroxime sodium powder
Guan Junwei. Study on compatible stability of shuanghuanglian powder injection and cefuroxime sodium powder[J]. Heilongjiang Medicine, 2011, 24(1): 92-93
Authors:Guan Junwei
Affiliation:Guan Junwei Sanjing Pharmaceutical Co.,Ltd,Harbin Pharmaceutical Group(150010)
Abstract:Objective:To study the compatible stability of shuanghuanglian powder injection and cefuroxime sodium powder.Methods:The samples of complexes with the Sodium chloride solution as a solvent were collected at room temperature to study the changes of appearanc,pH and to determine content by using HPLC method.Results:White precipitate produced and then content decreased after mixing Shuanghuanglian powder injection with cefuroxime sodium powder.Conclusion:Shuanghuanglian powder could not combine with cefuroxime sodium powder for injection.
Keywords:shuanghuanglian powder injection  compatible  stability  HPLC
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