糖尿病周围神经病变瘀血络损病机探微

糖尿病周围神经病变（DPN）在发病机理上既存在瘀血，同时也存在络损，其微血管病变及微循环障碍与神经生长因子减少，Na^ -K^ -ATP酶活性下降是瘀血络损这一中医学说提出的重要物质基础之一。故提出瘀血络损是DPN发病的病机关键，活血化瘀通络法是治疗DPN的根本法则，并阐述了瘀血络损在DNP发病中的作用，旨在完善和丰富DPN的中医病机理论，为DPN的治疗提供新的思路和途径。

An Exploration on the Pathogenesis of Blood - Stasis with Damaging Collaterals in Diabetic Peripheral Neuropathy

The author considered that the pathogenesis of diabetic peripheral neuropathy (DPN) is the simultaneous existence of blood-stasis and damage of collaterals, and the pathological change of micrangium, disturbance of microcirculation, decrease of nerve growth factor and the decrease of Na + - K+ - ATP ase are one of the important basis. Blood - stasis with damage of collaterals is the key of pathogenesis, and activating blood circulation and dredging the collaterals is the fundamental principle for the treament of DPN. The author also expounded the role of blood - stasis and collateral damage in the pathogenesis of DPN aiming at consummation and enrichment of TCM theory provide a new thinking and measure for the treatment.