甲亢患者的骨密度改变

目的 观察甲亢患者的ＢＭＤ改变及病程、ＴＴ３、年龄和性别对其改变的影响。方法 用单光子骨密度仪测量了１２９例未治甲亢患者桡骨ＢＭＤ。结果 甲亢组的桡骨ＢＭＤ低于正常对照组（Ｐ〈０．０１），ＢＭＤ减低发生率为２４．８０％。多元线性回归分析表明９０例女性甲亢患者的桡骨ＢＭＤ与病程及年龄呈负相关，而与ＴＴ３无关；３９例男性甲亢患者的桡骨ＢＭＤ与病程呈负相关，而与ＴＴ３和年龄无关。结论 甲 对骨质改变有重

Change of bone mineral density in the patient with hyperthyroidism

Objective To investigate the change of bone mineral density (BMD) and the effect of duration of disease, TT3, age and sex on BMD with hyperthyroidism. Methods 129 untreated cases with hyperthyroidism radius BMD were determined by single photon absortionmetry (SPA), and compared with normal control group. Results BMDs of radius in the cases with hyperthyroidism were lower than those of the normal control group( P <0.01). The BMD reducing rate was 24.80%. Multiple linear regression showed that there was negative correlation between BMD and both duration of disease and age, but no correlation between BMD and TT3, in 90 female cases with hyperthyroidism. There was negative correlation between BMD and duration of disease,but no correlation between BMD and both TT3 and age in 39 male cases with hyperthyroidism. Conclusion There was a significant effect of hyperthyroidism on the change of BMD. Duration of hyperthyroidism was the most important factor to causes BMD reducing,BMD of female patients were affected by both duration and age.