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Severe Pediatric Adenovirus 7 Disease in Singapore Linked to Recent Outbreaks across Asia |
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| Authors: | Oon Tek Ng Koh Cheng Thoon Hui Ying Chua Natalie Woon Hui Tan Chia Yin Chong Nancy Wen Sim Tee Raymond Tzer Pin Lin Lin Cui Indumathi Venkatachalam Paul Anantharajah Tambyah Jonathan Chew Raymond Kok Choon Fong Helen May Lin Oh Prabha Unny Krishnan Vernon Jian Ming Lee Boon Huan Tan Sock Hoon Ng Pei Jun Ting Sebastian Maurer-Stroh Vithiagaran Gunalan Wei Xin Khong |
| Abstract: | During November 2012–July 2013, a marked increase of adenovirus type 7 (Ad7) infections associated with severe disease was documented among pediatric patients in Singapore. Phylogenetic analysis revealed close genetic links with severe Ad7 outbreaks in China, Taiwan, and other parts of Asia. |
| Keywords: | Human adenovirus viruses Ad7 outbreak Asia China Singapore Malaysia invasive disease death mechanical ventilation |