加味天雄散治疗少弱精子症的疗效观察

目的观察加味天雄散治疗少弱精子症的有效性和安全性。方法将80例少弱精子症患者随机分为两组,治疗组40例,采用加味天雄散进行治疗,对照组40例,采用五子衍宗丸治疗。3个月为1个疗程。分别于治疗前后对患者进行综合疗效评价、精液参数分析及精子正常形态判定。结果完成观察70例,本研究临床疗效判定:治疗组总有效率91.43%,配偶妊娠率为8.57%,显效率65.71%;对照组总有效率85.71%,妊娠率为5.71%,显效率54.29%,治疗组总有效率和显效率均高于对照组,但差异无统计学意义(P0.05);两组均能显著提高精子密度、精子活力、精子正常形态百分率,治疗组优于对照组(P0.05,P0.01)。结论加味天雄散治疗少弱精子症有显著的疗效,能显著提高精子密度、精子活力,提高精子正常形态,减少头部畸形率,且安全性良好。

Effect of Modified Tianxiong Powder in Treating Oligospermia and Asthenospermia

Objective To investigate the clinical efficacy and safety of modified Tianxiong Powder （MTP） in treating oligospermia and asthenospermia. Methods Eighty patients were equally randomized into two groups, the treated group administered with MTP, and the controlled group administered with Wuzi Yanzong Pill （WYP）, all for 3 months. The comprehensive efficacy was observed; and parameters of patients′ semen and figure of sperm were analyzed before and after treatment.Results The observation was completed in 70 patients. The total effective rate and markedly effective rate were 91.43% and 65.71%, respectively in the treated group, 85.71% and 54.29%, respectively in the control group, the pregnancy rate in their wives was 8.57% and 5.71%, respectively. Comparisons showed no statistical significance between groups （P0.05） . Significant elevated perm count in semen and more active sperms with significantly better spermic figure, were found in both groups. However, the improvements in the treatment group were superior to those in the control group （P0.05 or P0.01）. Conclusion MTP shows good efficacy and high safety in treating oligospermia and asthenospermia, and it could improve the spermic count, motility and figure, and reduce the head deformity rate.