| 鼻咽癌放疗对甲状腺功能的影响 |
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| 引用本文： | 戴幼艺,申良方,廖遇平,邓豪余,段华新. 鼻咽癌放疗对甲状腺功能的影响[J]. 中国现代医学杂志, 2004, 14(7): 115-117 |
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| 作者姓名： | 戴幼艺 申良方 廖遇平 邓豪余 段华新 |
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| 作者单位： | 1. 中南大学湘雅医院,放疗科,湖南,长沙,410008
2. 中南大学湘雅医院,核医学科,湖南,长沙,410008 |
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| 摘 要： | 目的研究鼻咽癌一、二程放疗对甲状腺功能的影响.方法对该院2000年9月～2003年6月共97例鼻咽癌患者进行前瞻性研究,分放疗前、一程放疗后、二程放疗后(复发再治)三组,采用放疗法测定血清游离三碘甲状腺原氨酸(FT3)、游离四碘原氨酸(FT4)及高敏促甲状腺激素(hTSH)水平.结果一、二程放疗后血清FT3、FT4值较放疗前水平降低,hTSH值无明显差异;二程放疗后血清FT3、FT4、hTSH值与一程放疗后比较无明显差异.追踪3～24个月,一程放疗后有2例发生甲状腺功能减退(甲减),发生率6.45%(2/31).二程放疗后3例发生甲减,发生率为10%(3/30).一、二程放疗后总甲减发生率为8.2%(5/61).结论鼻咽癌放疗对甲状腺功能有损伤,一、二程放疗对甲状腺功能损伤无程度上的差别.
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| 关 键 词： | 鼻咽癌 放射治疗 甲状腺 |
| 文章编号： | 1005-8982(2004)07-0115-03 |
Influence on thyroid after radiotherapy of nasopharyngeal cancer |
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| DAI You-yi ,SHEN Liang-fang ,LIAO Yu-ping ,DENG Hao-yu and DUAN Hua-xin. Influence on thyroid after radiotherapy of nasopharyngeal cancer[J]. China Journal of Modern Medicine, 2004, 14(7): 115-117 |
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| Authors: | DAI You-yi SHEN Liang-fang LIAO Yu-ping DENG Hao-yu DUAN Hua-xin |
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| Affiliation: | DAI You-yi 1,SHEN Liang-fang 1,LIAO Yu-ping 1,DENG Hao-yu 2 and DUAN Hua-xin 2 |
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| Abstract: | Objective:To study the influence on thyroid after radiotherapy of nasopharyngeal cancer.Methods:97patients were divided into three group:(1)before radiotherapy;(2)after one course of radiother-apy;(3)after two courses of radiotherapy and their serum FT3,FT4and hTSH were measured.Results:There is significant decrease in the values of FT3,FT4after radiotherapy,but there is no significant difference in hTSH between the patients pre-radiotherapy and pro-radiotherapy.The FT3,FT4and hTSH have no sig-nificant difference between group(2)and group(3).Conclusion:Radiotherapy can destroy thyroid but there are no difference of destroy degree between one course of radiotherapy and two courses of radiotherapy. |
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| Keywords: | nasopharyngeal cancer radiotherapy thyroid |
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