脑室出血40例的临床治疗分析

目的：探讨治疗脑室出血两种不同方法的临床疗效。方法：选择2010年2月～2011年2月本院神经外科住院治疗的脑室出血患者40例，其中，男性23例，女性17例，年龄26～65岁，平均53.8岁，根据随机的原则将患者分为治疗组和对照组各20例。治疗组患者选择双侧脑室穿刺外引流、尿激酶灌注联合脑脊液置换术，对照组患者单纯使用侧脑室穿刺外引流方法治疗。比较两组间治疗的有效率和死亡率，对比两组间患者脑室通畅时间、脑脊液转清时间及意识转清时间。结果：治疗组1例（5%）患者死亡，对照组5例（25%）患者死亡，两组间患者死亡率差异无统计学意义（P＞0.05）；治疗组有效率为80%，对照组有效率为45%，两组间治疗有效率差异有统计学意义（P＜0.05）。治疗组患者脑室通畅时间、脑脊液转清时间及意识转清时间均明显短于对照组，其差异有统计学意义（P0.05）. 结论：双侧脑室穿刺外引流、尿激酶灌注联合脑脊液置换术是治疗脑室出血的一种有效的方法。

Clinical analysis of 40 cases intraventricular hemorrhage

Objective： To investigate the clinical efficacy of two different methods in the treatment of intraventrieular hemorrhage. Methods： 40 patients with intraventricular hemorrhage who were treated in the neurosurgical department of our hospital from February 2010 to February 2011 were chosen, including 23 males and 17 females, aged 26 to 65 years, mean 53.8 years, the patients were randomly divided into treatment group and control group. Patients of the treatment group were treated with double-ventricle puncture and drainage, urokinase perfusion combined cerebrospinal fluid replacement, patients of the eoutrol group were treated with simple lateral puncture drainage. Compared the efficiency and mortality of the two groups, The time of the ventricular patency, CSF turned clear and the time of consciousness turned clear were also compared. Results： There was 1 patient （5%） died in the treatment group, and 5 patients （25%） died in the control group, there was no significant difference between the mortality of two groups （P〉0.05）. The effective rate in the treatment group was 80%, in the control group the rate was 45%, there was significant difference between the two groups （P〈0.05）. The time of the ventrieular patency, CSF turned clear and the time of consciousness turned clear in the treatment group were much shorter than those of the control group, the difference was statistically significant （P〈0.05）. Conclusion： Double ventricle puncture drainage, urokinase perfusion combined cerebrospinal fluid replacement is an effective treatment method in the treatment of intraventrieular hemorrhage.