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Free radical scavengers from the heartwood of Juniperus chinensis
Authors:Lim Jong Pil  Song Young Cheol  Kim Jin Wook  Ku Chung Hwan  Eun Jae Soon  Leem Kang Hyun  Kim Dae Keun
Institution:College of Pharmacy, Woosuk University, Samrye, Korea.
Abstract:The antioxidant activity of Juniperus chinensis (Cupressaceae) was determined by measuring the radical scavenging effect on DPPH (1,1-diphenyl-2-picrylhydrazyl). The methanolic extract of J. chinensis heartwood showed the strong antioxidant activity. The antioxidant activity of n-BuOH soluble fraction was stronger than that of the others, and the fraction was subjected to purification by repeated silica gel and Sephadex LH-20 column chromatography. Quercetin, naringenin, taxifolin, aromadendrin and isoquercitrin were isolated from the n-BuOH fraction. Their structures were elucidated by physico-chemical and spectroscopic studies.
Keywords:Juniperus chinensis  Antioxidant activity  Quercetin  Naringenin  Taxifolin  Aromadendrin  Isoquercitrin  DPPH radical
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