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树突状细胞与卵巢癌的免疫治疗
引用本文:梁婧,荣凤年,李岩.树突状细胞与卵巢癌的免疫治疗[J].国际肿瘤学杂志,2008,35(8):627-630.
作者姓名:梁婧  荣凤年  李岩
作者单位:1. 山东省千佛山医院肿瘤中心,济南,250014
2. 山东省千佛山医院妇产科,济南,250014
摘    要:树突状细胞(DC)是目前发现的体内功能最强的专职抗原提呈细胞,可在体内外激活初始T细胞,并有效诱发细胞毒性T淋巴细胞反应,在抗肿瘤免疫中发挥重要作用.近年来采用DC疫苗进行抗肿瘤治疗已成为肿瘤生物治疗领域的热点之一.DC抗肿瘤机制及DC疫苗在卵巢癌治疗中的应用等研究也取得了很大进展.

关 键 词:树突细胞  卵巢肿瘤  癌症疫苗  免疫疗法

Dendritic cell and immunotheray for ovarian cancer
Abstract:Dendritic cell (DC) is known the strongest professional antigen presenting cell (APC) in the organism at present, and may process the antigen to native T cell and induce cytotoxic T lymphocyte(CTL) response in vivo and in vitro, it plays a vital role in anti-tumor immunity. In recent years, anti-tumor treatment using DC vaccines has become one of the focuses of tumor biological treatment The research on DC anti-tumor mechanisms and application of DC vaccine in ovarian cancer have made a great progress.
Keywords:Dendritic cells  Ovarian neoplasms  Cancer vaccine  Immunotheray
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