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大叶石头花中的黄酮碳苷
引用本文:聂韡,罗建光,孔令义. 大叶石头花中的黄酮碳苷[J]. 中国天然药物, 2010, 0(4): 250-252
作者姓名:聂韡  罗建光  孔令义
作者单位:中国药科大学天然药物化学教研室,南京210009
基金项目:【基金项目】国家杰出青年科学基金(No.30525032)
摘    要:目的:研究大叶石头花地上部分的黄酮碳苷成分。方法:用70%乙醇回流提取,氯仿和正丁醇依次萃取,采用硅胶、SephadexLH-20、ODS柱色谱等方法分离纯化,根据理化性质和光谱数据鉴定化合物的结构。结果:从大叶石头花地上部分分离得到6个黄酮碳苷:皂草黄素(isovitexin,1),芒果素(mangiferin,2),异荭草素(isoorientin,3),2''-O-鼠李糖基-7-甲氧基异荭草素(4),2''-O-鼠李糖基皂草黄素(5),2''-O-鼠李糖基异荭草素(6)。结论:化合物1~6首次从该属中分离得到。

关 键 词:大叶石头花  石竹科  黄酮碳苷

C-Glycosylflavonoids from the Aerial Part of Gypsophila pacifica
NIE Wei,LUO Jian-Guang,KONG Ling-Yi. C-Glycosylflavonoids from the Aerial Part of Gypsophila pacifica[J]. Chinese JOurnal of Natural Medicines, 2010, 0(4): 250-252
Authors:NIE Wei  LUO Jian-Guang  KONG Ling-Yi
Affiliation:* Department of Natural Medicinal Chemistry,China Pharmaceutical University,Nanjing 210009,China
Abstract:AIM:To study the C-glycosylflavonoids from the aerial parts of Gypsophila pacifica Kom.METHODS:The C-glycosylflavonoids were isolated by various column chromatographic methods and their structures were identified by spectral data together with physicochemical analysis.RESULTS:Six known compounds were isolated and identified as isovitexin(1),mangiferin(2),isoorientin(3),2''-O-rhamnopyransoyl-7-methoxylisoorientin(4),2''-O-rhamnopyransoyl-isovitexin(5),and 2''-O-rhamnopyransoyl-isoorientin(6).CONCLUSION:The six compounds were isolated from the genus Gypsophila for the first time.
Keywords:Gypsophila pacifica  Caryophyllaceae  C-Glycosylflavonoids
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