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草豆蔻的化学成分(英文)
引用本文:王小兵,杨长水,华淑贞,孔令义.草豆蔻的化学成分(英文)[J].中国天然药物,2010(6):419-421.
作者姓名:王小兵  杨长水  华淑贞  孔令义
作者单位:中国药科大学天然药物化学教研室,南京210009
基金项目:国家自然科学基金(No.21072230);江苏省自然科学基金创新学者攀登项目(No.BK2008039)
摘    要:目的:研究草豆蔻的化学成分。方法:采用硅胶和Sephadex LH-20柱色谱方法进行化合物的分离和纯化, 根据理化性质和光谱数据鉴定化合物结构。结果:从草豆蔻提取物中分离得到了10个化合物, 经鉴定分别为:1, 7-双苯-5-羟基-4, 6-庚烯-3-酮 (trans, trans-1, 7-diphenyl-5-hydroxy-4, 6-hepten-3-one, 1), 乔松素 (pinocembrin, 2), 山姜素 (alpinetin, 3), 7, 4′-二羟基-5-甲氧基二氢黄酮 (4), 蜡菊亭(helichrysetin, 5), 2′, 4′-二羟基-6′-甲氧基二氢查尔酮 (uvangoletin, 6), (1E, 4Z)-5-hydroxy-1-phenylhexa-1, 4-dien-3-one (7), katsumadain B(8), 羊踯躅素I(rhodomollein I, 9)和金色酰胺醇酯(aurantiamide acetate,10)。结论:化合物7为一个新天然产物, 化合物9和10为首次从该属中分离得到。

关 键 词:草豆蔻  黄酮  化学成分

Chemical Constituents from the Seeds of Alpinia katsumadai Hayata
WANG Xiao-Bing,YANG Chang-Shui,HUA Shu-Zhen,KONG Ling-Yi.Chemical Constituents from the Seeds of Alpinia katsumadai Hayata[J].Chinese JOurnal of Natural Medicines,2010(6):419-421.
Authors:WANG Xiao-Bing  YANG Chang-Shui  HUA Shu-Zhen  KONG Ling-Yi
Institution:Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China
Abstract:AIM: To investigate the chemical constituents from the seeds of Alpinia katsumadai Hayata. METHODS: Compounds were isolated and purified by column chromatography with silica gel and Sephadex LH-20, and their structures were identified on the basis of physiochemical properties and spectroscopic data. RESULTS: Ten compounds are isolated and elucidated as trans, trans-1, 7-diphenyl-5-hydroxy-4,6-hepten-3-one (1), pinocembrin (2), alpinetin (3), 7, 4′-dihydroxy-5-methoxy flavanone (4), helichrysetin (5), uvangoletin (6), (1E, 4Z)-5-hydroxy-1-phenyl-hexa-1, 4-dien-3-one (7), katsumadain B (8), rhodomollein I (9), and aurantiamide acetate (10). CONCLUSION: Compound 7 was a new natural product. Compounds 9 and 10 were isolated from the genus for the first time.
Keywords:Alpinia katsumadai Hayata  Flavonoids  Chemical constituents
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