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薄叶红厚壳根的呫吨酮成分(英文)
引用本文:虞俊,宋鑫明,陈光英,韩长日,赵军,尹奇伟. 薄叶红厚壳根的呫吨酮成分(英文)[J]. 中国天然药物, 2010, 0(6): 433-435
作者姓名:虞俊  宋鑫明  陈光英  韩长日  赵军  尹奇伟
作者单位:海南师范大学“省部共建-热带药用植物化学”教育部重点实验室,化学与化工学院,海口571158
基金项目:国家自然科学基金资助课题(Nos.20862005和20562004);新世纪高校优秀人才计划(NCET-08-0656)
摘    要:目的:研究薄叶红厚壳根的乙酸乙酯部位的化学成分。方法:运用各种色谱方法进行化学成分的分离纯化, 用理化方法和波谱数据解析其化学结构。结果:分离得到 11 个呫吨酮,结构分别为 1, 7-二羟基-3-甲氧基呫吨酮(1), 1, 5, 6-三羟基呫吨酮(2), 1, 3, 6-三羟基-5-甲氧基呫吨酮(3), 1, 3, 7-三羟基呫吨酮(4), 1-羟基-6, 7-二甲氧基呫吨酮(5), 3, 5-二羟基呫吨酮(6), 4-羟基-3-甲氧基呫吨酮(7), 1, 2-二甲氧基呫吨酮(8), 1, 3, 5-三羟基呫吨酮(9), pyranojacareubin(10), 1, 4, 5-三羟基呫吨酮(11)。结论:所有的化合物均为首次从该植物中分离得到, 其中 1, 3-7, 9 为首次从该属植物中分离得到。

关 键 词:化学成分  呫吨酮  薄叶红厚壳  藤黄科

Xanthones from the Roots of Calophyllum membranaceum
YU Jun,SONG Xin-Ming,CHEN Guang-Ying,HAN Chang-Ri,ZHAO Jun,YIN Qi-Wei. Xanthones from the Roots of Calophyllum membranaceum[J]. Chinese JOurnal of Natural Medicines, 2010, 0(6): 433-435
Authors:YU Jun  SONG Xin-Ming  CHEN Guang-Ying  HAN Chang-Ri  ZHAO Jun  YIN Qi-Wei
Affiliation:Key Laboratory of Tropical Medicinal Plant Chemistry, Ministry of Education, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, China
Abstract:AIM: To investigate chemical components of the ethyl acetate fraction of Calophyllum membranaceum. METHODS: Isolation and purification were carried out by several column chromatographic methods. Compounds were identified based on their physicochemical properties and spectral data. RESULTS: Eleven xanthones were isolated from ethanol extract of the roots of C. Membranaceum. The structures of those xanthones were elucidated as 1, 7-dihydroxy- 3-methoxyxanthone (1), 1, 5, 6-trihydroxyxanthone (2), 1, 3, 6-trihydroxy-5-methoxy-xanthone (3), 1, 3, 7-trihydroxyxanthone (4), 1-hydroxy-6, 7-dimethoxyxanthone (5), 3, 5-dihydroxyxanthone (6), 4-hydroxy-3-methoxy xanthone (7), 1, 2-dimethoxyxanthone (8), 1, 3, 5-trihydroxyxanthone (9), pyranojacareubin (10), and 1, 4, 5-trihydroxyxanthone (11). CONCLUSION: All compounds are firstly isolated from this plant and compounds 1, 3-7, 9 were isolated from the Calophyllum genus for the first time.
Keywords:Chemical components  Xanthones  Calophyllium membranaceum  Guttiferae
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