| 苣荬菜的甾体和酚类化学成分 |
| |
| 引用本文： | 夏正祥,梁敬钰.苣荬菜的甾体和酚类化学成分[J].中国天然药物,2010(4):267-269. |
| |
| 作者姓名： | 夏正祥 梁敬钰 |
| |
| 作者单位： | 中国药科大学天然药物化学教研室,南京210009 |
| |
| 摘 要： | 目的：研究苣荬菜的甾体和酚类化学成分,为阐明其有效成分和植物化学分类学提供依据。方法：采用硅胶、Sephadex-LH-20及Rp-18等柱层析色谱方法进行化合物的分离纯化,应用波谱解析和理化常数对照方法鉴定其结构.结果：分离得到11个化合物,分别鉴定为：麦角甾-6,22-二烯-3β,5α,8α-三醇（1）,豆甾-5-烯-3β,7α-二醇（2）,豆甾-5,22-烯-3β,7α-二醇（3）,豆甾-7,22-二烯-3β,5α,6β-三醇（4）,豆甾-6β-羟基-4,22-二烯-3-酮（5）,谷甾醇（6）,胡萝卜苷（7）,异东莨宕葶（8）,七叶内酯（9）,大黄素（10）,洋芹素（11）。结论：化合物1-5,8-10均为首次从该属植物中分离得到,此类甾体和酚醇可作为该属植物化学分类学依据。
|
| 关 键 词： | 苣荬菜 甾体 酚醇 化学成分 |
Steroids and Phenols from Sonchus arvensis |
| |
| XIA Zheng-Xiang,LIANG Jing-Yu.Steroids and Phenols from Sonchus arvensis[J].Chinese JOurnal of Natural Medicines,2010(4):267-269. |
| |
| Authors: | XIA Zheng-Xiang LIANG Jing-Yu |
| |
| Institution: | ＊ Department of Natural Medicinal Chemistry,China Pharmaceutical University,Nanjing 210009,China |
| |
| Abstract: | AIM：To investigate the chemical constituents of Sonchus arvensis L.METHODS：Compounds were isolated and purified by various chromatographic techniques,and their structures were elucidated by physicochemical properties and spectroscopic data.RESULTS：Eleven chemical constituents were isolated and identified as ergost-6,22-diene-3β,5α,8α-triol（1）,stigmast-5-ene-3β,7α-diol（2）,stigmasta-5,22-dien-3β,7β-diol（3）,3β,5α,6β-trihydroxy-stigmast-7,22-diene（4）,stigmast-6β-hydroxy-4,22-diene-3-one（5）,β-sitosterol（6）,daucosterol（7）,isoscopoletin（8）,aesculetin（9）,emodin（10）,and apigenin（11）.CONCLUSION：Compounds 1-5,8-10 were isolated from the genus Sonchus for the first time,which could be significant from the chemotaxonomic point of view. |
| |
| Keywords: | Sonchus arvensis Steroid Phenol Chemical constituents |
| 本文献已被 维普 等数据库收录！ |
|
