| 家兔棘阿米巴角膜炎动物模型的建立 |
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| 引用本文： | 邓新国,郭雪,庞广仁,田小莉.家兔棘阿米巴角膜炎动物模型的建立[J].中国寄生虫学与寄生虫病杂志,1999,17(5):308-310. |
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| 作者姓名： | 邓新国 郭雪 庞广仁 田小莉 |
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| 作者单位： | 河南省眼科研究所!郑州450003(邓新国，庞广仁，田小莉)，河南省卫生防疫站!郑州450003(郭雪) |
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| 摘 要： | 目的:建立棘阿米巴角膜炎的动物模型。方法:在6 只新西兰家兔角膜基质层内注射地塞米松3 d 后,再注入棘阿米巴原虫悬液。结果:6 只家兔均发生角膜炎。经家兔角膜刮片用10% 氢氧化钾封片镜检、角膜组织原虫培养和病理切片染色检查证实,成功地建立了家兔棘阿米巴角膜炎动物模型。结论:通过角膜基质内注射建立的家兔棘阿米巴角膜炎动物模型,方法简便又易于操作
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| 关 键 词： | 棘阿米巴角膜炎 基质内注射 动物模型 |
ESTABLISHMENT OF A RABBIT MODEL OF ACANTHAMOEBA KERATITIS |
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| DENG Xinguo,GUO Xue,PANG Guangren,TIAN Xiaoli.ESTABLISHMENT OF A RABBIT MODEL OF ACANTHAMOEBA KERATITIS[J].Chinese Journal of Parasitology and Parasitic Diseases,1999,17(5):308-310. |
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| Authors: | DENG Xinguo GUO Xue PANG Guangren TIAN Xiaoli |
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| Institution: | Henan Institute of Ophthalmology, Zhengzhou 450003. |
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| Abstract: | AIM: To establish an animal model of Acanthamoeba keratitis. METHODS:Six New Zealand white rabbits were each injected intrastromally with Acanthamoeba suspension 3 days after subconjunctival injection with dexamethasone. RESULTS:All of the 6 rabbits developed keratitis. Acanthamoeba protozoa were identified by the methods of corneal scraping with 10% potassium hydroxide wet mount examined under microscope,corneal protozoa culture and pathological section examination. CONCLUSION:A rabbit model of Acanthamoeba keratitis was established. |
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| Keywords: | Acanthamoeba keratitis animal model intrastromal injection |
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