卫氏并殖吸虫童虫的生物学特性

目的： 了解卫氏并殖吸虫童虫的生物学特性。方法： 从锯齿华溪蟹分离卫氏并殖吸虫囊蚴, 以每鼠８０～１５０ 个囊蚴感染小鼠和大鼠, 分别于感染后１０～３０ ｄ 和８０～５８０ ｄ 分期解剖小鼠和大鼠, 检查虫体。观察童虫的寿命、在死亡宿主或５～８ ℃生理盐水中, 存活的时间及对新宿主的侵袭力。结果： 童虫的寿命较长, 大鼠于感染囊蚴５８０ ｄ 死亡后检出的童虫仍可转种其它大鼠; 同样, 小鼠体内的童虫也可转种其它小鼠, 童虫寿命不受某一个体宿主寿命限制。在转续宿主间转换, 可延长童虫的寿命, 并保持其活力和侵袭力。死亡小鼠体内的童虫及低温保存的童虫, 仍有较强的活力与侵袭力。结论： 童虫具有较强的活力与侵袭力, 为卫氏并殖吸虫的感染期

BIOLOGICAL CHARACTERISTICS OF THE JUVENILE PARAGONIMUS WESTERMANI

AIM: To observe the biological characteristics of the juvenile of Paragonimus westermani. METHODS: Kunmin strain mice and Wistar rats inoculated orally with 100-150 metacercariae of Paragonimus westermani were autopsied 10-30 days and 80-580 days after infection, respectively. Life-span, survival time in dead hosts or physiological saline at 5 degrees C to 8 degrees C and invasiveness of juveniles to new hosts were detected by host transfer. RESULTS: All the worms recovered from the mice and rats were stunted juveniles. The worm detection rates in the mice and rats were 19.3% and 22.2%-37.5%, respectively. The life-span of the juveniles was rather long, being not limited by the life-span of a host. Host transfer could prolong longevity and preserve invasiveness. The juveniles recovered from dead mice still possess strong vitality and invasiveness. CONCLUSION: The juvenile of P. westermani is an infective stage, having strong vitality and invasiveness.