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Real-time contrast-enhanced ultrasound imaging of focal liver lesions in fatty liver
Authors:Guang-Jian Liu  Wei Wang  Xiao-Yan Xie  Hui-Xiong Xu  Zuo-Feng Xu  Yan-Ling Zheng  Jin-Yu Liang  Fuminori Moriyasu  Ming-De Lu
Institution:1. Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China;2. Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan;3. Department of Hepatobiliary Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
Abstract:PurposeThe objective of this study was to investigate the contrast-enhanced ultrasound (CEUS) imaging features of focal liver lesions (FLLs) in fatty liver.MethodOne hundred FLLs in 98 patients with fatty liver were evaluated with real-time CEUS.ResultsAll malignant FLLs showed hyperenhancement in arterial phase and contrast washout in portal and late phases. Among the FLLs, 3.3% of hemangiomas, 12.5% of focal nodular hyperplasias (FNHs), and 2.5% of focal fatty sparing lesions showed contrast washout in the late phase. The sensitivity and specificity for the characterization of hepatocellular carcinoma, metastasis, hemangioma, FNH, and focal fatty sparing lesions were 100% and 95.6%, 60% and 100%, 93.3% and 98.6%, 87.5% and 97.8%, and 92.6% and 100%, respectively.ConclusionsCorrect characterization of FLLs in fatty liver by CEUS is possible based on their typical enhancement patterns.
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