| Observations on Therapeutic Effects of Huangdan Decoction and Tripterygium Wilfordii Compound Tablet on Membranous Glomerulon |
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| 引用本文： | 郑坚峰,陈思源.Observations on Therapeutic Effects of Huangdan Decoction and Tripterygium Wilfordii Compound Tablet on Membranous Glomerulon[J].华中科技大学学报(医学英德文版),1995(1). |
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| 作者姓名： | 郑坚峰 陈思源 |
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| 作者单位： | Department of Traditional Chinese Medicine，Xiehe Hospital，Tongji Medical University，Wuhan |
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| 摘 要： | （郑坚峰）（陈思源）ＯｂｓｅｒｖａｔｉｏｎｓｏｎＴｈｅｒａｐｅｕｔｉｃＥｆｆｅｃｔｓｏｆＨｕａｎｇｄａｎＤｅｃｏｃｔｉｏｎａｎｄＴｒｉｐｔｅｒｙｇｉｕｍＷｉｌｆｏｒｄｉｉＣｏｍｐｏｕｎｄＴａｂｌｅｔｏｎＭｅｍｂｒａｎｏｕｓＧｌｏｍｅｒｕｌｏｎｅｐｈｒ...
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Observations on Therapeutic Effects of Huangdan Decoctionand Tripterygium Wilfordii Compound Tablet on Membranous Glomerulonephritis in Rats |
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| ZHENG Jian-feng,CHEN Si-yuan.Observations on Therapeutic Effects of Huangdan Decoctionand Tripterygium Wilfordii Compound Tablet on Membranous Glomerulonephritis in Rats[J].Journal of Zuazhong University of Science and Technology: Medical Edition,1995(1). |
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| Authors: | ZHENG Jian-feng CHEN Si-yuan |
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| Abstract: | The model of membranous glomerulonephritis(MGN)in rats was successfully established using self-made cationic bovine serum albumin(C-BSA)and treated with Huangdan Decoction (HDD) and Tripterygium Wilfordii Co.tablet(TW).Results indicated that the levels of urinary protein,blood urea nitrogen(BUN)and serum creatinine(Scr) in treated groups(groups A,B and C)were significantly decreased as compared with the control group(group D)(PM0.01).By light and electron microscope and immunofluorescent technique,the damage to kidney in groups A,B and C was found much milder than that in group D with lesion in group A being slightest.These findings suggest that HDD and TW may alleviate the pathological lesions of MGN,prevent or retard its progression,and have remarkable therapeutic effects on MGN. |
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| Keywords: | membranous glomerulonephritis(MGN) Huangdan Decoction(HDD) Tripterygium wilfordii Co tablet(TW) |
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