Update on smoking cessation therapies |
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Authors: | Deirdre A. Glynn John F. Cryan Pauline Kent Robert A. Flynn Marcus P. Kennedy |
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Affiliation: | (1) Department of Medicine, Sligo General Hospital, The Mall, Co. Sligo, Sligo, Republic of Ireland;(2) Department of Pharmacology and Therapeutics, School of Pharmacy, University College Cork, Cork, Republic of Ireland |
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Abstract: | As a reflection of an exponential increase in smoking rates throughout the world during the last century, the economic and human burden of mortality and morbidity related to smoking is now clearly defined. Smoking cessation is associated with health benefits for people of all ages. In this paper we provide a comprehensive review of current licensed pharmacological smoking cessation agents including efficacy and safety profiles, with comparisons of individual therapies available. Furthermore, we offer a prospective on the need for further testing of other agents including novel avenues of therapy. |
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Keywords: | antidepressant bupropion chronic obstructive pulmonary disease ischemic heart disease lung cancer nicotine smoking tobacco vaccination varenicline |
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