早产儿视网膜病变发病情况分析

目的 分析早产儿视网膜病变(ROP)的发病情况.方法 回顾性分析2005年9月至2008年5月来就诊的胎龄小于36周、体重低于2500g的210例早产儿的眼底筛查情况及高危因素.结果 210例早产儿中,ROP的发生率为12.9%,其中ROP3期以上的发生率为3.8%;低孕周、低体重、出生后吸氧时间过长、严重的新生儿疾病的早产儿ROP发生率高;双生子ROP发生率(20.5%)高于单生子(10.8%),且ROP发生严重.结论 低孕周、低体重、出生后吸氧时间过长、患严重的新生儿疾病、非单生子等是引起早产儿视网膜病变的高危因素.

Analysis of retinopathy of prematurity

Objective To analyze the incidence and severity of retinopathy of prematurity (ROP). Methods A retrospective analysis was conducted on 210 premature children from September 2005 to May 2008 with weight equal to or less than 2500g or a gestational age at birth of 36 weeks or less.All of the mem-bers were examined by indirect binocular ophthalmoscopy.Results ROP occurred with an incidence rate of 12.9% among 210 premature children, and above ROP stages Ⅲ occurred with an incidence rate of 3.8%, This study showed the infants were more prone to develop ROP with short geststional age, low birth weight,long time of oxygen inhalation, and severe infants diseases.Twins had a significantly higher rate of ROP (20.5%) than singleton babies(10.8%), ROP were severer in twins than singleton babies.Conclusion Short gestational age, low birth weight, long time of oxygen inhalation, severe infants diseases, and non-singleton babies were the most significant factors associated with ROP.