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Liu Wei Di Huang Wan, a well-known traditional Chinese medicine, induces CYP1A2 while suppressing CYP2A6 and N-acetyltransferase 2 activities in man |
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| Authors: | Yao Chen Zhen Kang Jin Yan Zhi-Rong Tan Dong-Sheng Ouyang |
| Institution: | a Institute of Clinical Pharmacology, Central South University, 110 Xiang-Ya Road, Changsha, Hunan 410078, China b Children Hospital of Hunan Province, Changsha, Hunan 410007, China c The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China |
| Abstract: | |
| Keywords: | LDW Liu Wei Di Huang Wan CYP450 CYP450 monooxygenase system CYP1A2 cytochrome P4501A2 CYP2A6 cytochrome P4502A6 NAT2 N-acetyltransferase 2 XO xanthine oxidase 17X 1 7-dimethylxanthine 17U 1 7-dimethylurate 1X 1-methylxanthine 1U 1-methylurate AFMU 5-acetylamino-6-formylamino-3-methyluracil UCMR urinary caffeine metabolite ratio |
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