Benign breast disease, recent alcohol consumption, and risk of breast cancer: a nested case-control study |
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| Authors: | Rulla M Tamimi Celia Byrne Heather J Baer Bernie Rosner Stuart J Schnitt James L Connolly Graham A Colditz |
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| Affiliation: | (1) Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA;(2) Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA;(3) Cancer Genetics and Epidemiology Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA;(4) Department of Biostatistics, Harvard School of Public Health, Boston, MA, USA;(5) Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA;(6) Harvard Center for Cancer Prevention, Boston, MA, USA |
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| Abstract: | Introduction Alcohol consumption is a well-established risk factor for breast cancer. Some studies have suggested that the risk of breast cancer associated with alcohol consumption is greater for women with a history of benign breast disease (BBD). We hypothesized that among women with biopsy-confirmed BBD, recent alcohol consumption would increase the risk of breast cancer in women with proliferative breast disease to a greater extent than in women with nonproliferative breast disease. |
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