| FL抗肿瘤效果的研究进展 |
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| 引用本文： | 董坚,王朝辉. FL抗肿瘤效果的研究进展[J]. 昆明医学院学报, 2004, 25(3): 86-89 |
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| 作者姓名： | 董坚 王朝辉 |
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| 作者单位： | 1. 昆明医学院第一附属医院临床医学研究中心,昆明,650031
2. University of Cininnati,Ohio 45265,USA |
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| 摘 要： | Flt3-ligand(FL)细胞因子具有诱导骨髓系和淋巴系造血干细胞增殖和分化的功能，与同类细胞因子比较，它能在体内和体外大量增殖树突细胞(dendritic cells,DCs)的特殊功效使其具有良好的抗肿瘤潜力．现就FL的基因的生物结构、抗肿瘤的动物研究和临床应用潜力进行综述．
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| 关 键 词： | 抗肿瘤 临床应用 细胞因子 增殖 FL Flt3 淋巴 动物研究 基因 生物结构 |
| 文章编号： | 1003-4706(2004)03-0086-04 |
| 修稿时间： | 2004-05-10 |
Research Progress of FL in Antitumor Response |
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| DONG jian ),WANG Chao-hui ). Research Progress of FL in Antitumor Response[J]. Journal of Kunming Medical College, 2004, 25(3): 86-89 |
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| Authors: | DONG jian ) WANG Chao-hui ) |
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| Affiliation: | DONG jian 1),WANG Chao-hui 2) |
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| Abstract: | Flt3-ligand (FL) is a growth factor that was discovered by its ability to stimulate the proliferation of hematopoietic progenitor cells of both lymphoid and myeloid origin. The remarkable activity of FL to induce large numbers of dendritic cells (DCs) both in vivo and in vitro soon captured the interest of numerous researchers. In this review, we examine the structure and function of the FL, its antitumor activity in animal models, and its potential as a novel cancer treamtment. |
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| Keywords: | FL DCs Antitumor response |
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