肝移植治疗原发性肝癌

目的　对肝移植治疗原发性肝癌方案进行改进。方法　回顾性分析 2 1例肝移植治疗原发性肝癌的病例资料。结果　手术死亡 2例 ,手术死亡率为 9 5 2 % ;肝动脉血栓形成 1例 ,腹腔内出血 1例 ;2例分别于术后 13个月、18个月死于肝癌复发、肝癌肺部转移。现 16例无瘤生存 ,其中 1例存活超过 3年 ,4例存活超过 2年 ,7例存活超过 1年。结论　病肝切除方法、免疫抑制方案、术后化疗方案的改进可能是提高疗效的原因

LIVER TRANSPLANTATION TREATING PRIMARY HEPATOCELLULAR CARCINOMA

Objective: To report the innovation of liver transplantation treating primary hepatocellular carcinoma and its results. Methods: The clinical data of 21 cases liver transplantation treating primary hepatocellular carcinoma were analyzed retrospectively from Jan, 1999 to Oct, 2002. Results: Two patients died postoperatively. The mortality rate of this group was 9 52%. Complications: hepatic artery thrombosis(1 case); intraperitoneal bleeding (1 case). Two recipients died of recurrence and pulmonary metastasis of primary hepatocellular carcinoma in the thirteen and eighteen months after the operations respectively. Sixteen recipients survived without recurrence. One recipient survived for more than three years, four recipients survived for more than two years and seven recipients survived for more than one year. Conclusions: The innovation of the resection of cirrhotic liver, immunosuppression protocol and postoperative chemotherapy protocol may be the causes of satisfied results in this study.