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基于中药质量标志物(Q-Marker)的鹿茸质量控制标准体系构建
引用本文:宫瑞泽,陆雨顺,张磊,李志满,李珊珊,孙印石. 基于中药质量标志物(Q-Marker)的鹿茸质量控制标准体系构建[J]. 中草药, 2021, 52(9): 2851-2862
作者姓名:宫瑞泽  陆雨顺  张磊  李志满  李珊珊  孙印石
作者单位:中国农业科学院特产研究所, 吉林 长春 130112
基金项目:国家重点研发计划项目(2018YFC1706604);国家重点研发计划项目(2018YFC1706605);中国农业科学院科技创新工程项目(CAAS-ASTIP-2016-ISAPS);吉林省科技发展计划项目(20180201076YY)
摘    要:鉴于鹿茸质量控制存在基原复杂、品种混乱,质量评价标准匮乏等问题,鹿茸质量控制标准体系建设亟待加强.中药质量标志物(qualitymarker,Q-Marker)的提出及鹿茸中一些相对特异的化学成分逐渐被科学家们发现,为鹿茸质量评价提供了新的契机.详细概括了目前鹿茸质量控制存在的问题,深度辨析了鹿茸Q-Marker的筛选...

关 键 词:鹿茸  质量控制  质量标志物  五原则  羟脯氨酸  硫酸软骨素  γ-氨基丁酸  生产全过程质量控制  质量控制标准体系
收稿时间:2020-08-30

Establishment of quality control standard system for Cervi Cornu Pantotrichum based on quality marker (Q-Marker) of traditional Chinese medicine
GONG Rui-ze,LU Yu-shun,ZHANG Lei,LI Zhi-man,LI Shan-shan,SUN Yin-shi. Establishment of quality control standard system for Cervi Cornu Pantotrichum based on quality marker (Q-Marker) of traditional Chinese medicine[J]. Chinese Traditional and Herbal Drugs, 2021, 52(9): 2851-2862
Authors:GONG Rui-ze  LU Yu-shun  ZHANG Lei  LI Zhi-man  LI Shan-shan  SUN Yin-shi
Affiliation:Institute of Special Animal and Plant Science, Chinese Academy of Agricultural Sciences, Changchun 130112, China
Abstract:In view of the problems of quality control for Cervi Cornu Pantotrichum (CCP), such as complex origins, chaotic varieties, and lack of quality evaluation standards, the construction of quality control standard system for CCP needs to be strengthened urgently. Introduction of quality marker (Q-Marker) of traditional Chinese medicine and discovery of some relatively specific chemical components in CCP by scientists provide a new opportunity for the quality evaluation of CCP. The current problems of quality control for CCP are summarized in detail, the selection principles of Q-Marker in CCP are deeply analyzed, and a quality evaluation standard system for CCP are systematically established in this paper, which provides a guarantee for the promotion of quality control standards for CCP and the standardization of the deer industry market, and also benefits of the healthy and orderly development of the deer industry.
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