早产儿视网膜病变自然消退儿童的视功能发育研究

目的 研究早产儿视网膜病变(ROP)自然消退儿童的视功能发育情况.方法 回顾性收集ROP自然消退儿童238例(476眼)为观察组,并根据检查时年龄分为3～≤4岁组72例(144眼),4～≤5岁组65例(130眼),5～≤6岁组101例(202眼).以同期未发生ROP的儿童262例(524眼)作为对照组,其中3～≤4岁组...

A study on the development of visual function in children with spontaneous regression of retinopathy of prematurity

Objective To study the development of visual function in children with spontaneous regression of retinopathy of prematurity(ROP).Methods A total of 238 children with spontaneous regression of ROP(476 eyes)were retrospectively collected as the observation group.According to the ages of the patients at the time of examination,they were divided into 3-≤4 years old group(n=72,144 eyes),4-≤5 years old group(n=65,130 eyes),and 5-≤6 years old group(n=101,202 eyes).A total of 262 children(524 eyes)without ROP in the same period were taken as the control group,including 89 cases(178 eyes)of the 3-≤4 years old group,82 cases(164 eyes)of the 4-≤5 years old group,and 91 cases(182 eyes)of the 5-≤6 years old group.The refractive status,biological parameters and macula central foveal thickness of the children′eyes at different ages were measured and compared between the two groups.Results There were no statistically significant differences in the refractive status,biological parameters(except axial length and anterior chamber depth)and macula central foveal thickness of the eyes between the two groups(P>0.05).Among the different age groups,there were statistically significant differences in the diopter of spherical power,axial length,anterior chamber depth,lens thickness and macular foveal retinal thickness(P<0.05).Conclusion Compared with the children without ROP,the children with spontaneously regressed ROP have no significant differences in the refractive status,biological parameters and macula central foveal thickness of the eyes from age 3 to 6.They are mainly emmetropia and hyperopia,and the development of eyeballs is not significantly affected.Attention should be paid to the existence of visual dysfunction in children with spontaneous regression of ROP,and the monitoring and treatment of visual function should be strengthened during their growth process to protect the development of visual function to the greatest extent.