决明子的化学成分、药理作用及质量标志物预测分析

决明子是我国传统中药材,具有食用和药用双重价值,主要分布于长江以南地区,主产于安徽、广西、四川等地.近年来,随着决明子在药品及保健用品中应用越来越广泛,其多种类型化学成分及药理作用研究逐步深入.在对决明子化学成分、药理作用进行综述的基础上,结合中药质量标志物(qualitymarker,Q-Marker)概念,从植物亲...

Research progress on chemical composition and pharmacological effects of Cassiae Semen and predictive analysis on quality markers

Cassiae Semen is a traditional Chinese medicinal material in China, which has both value of edible and medicinal values. It is mainly distributed in the south area of the Yangtze River and produced in Anhui, Guangxi, Sichuan and other places. In recent years, with the wide application of Cassiae Semen in medicine and health care products, the research on its multi-types of chemical components and pharmacological effects has been deepened step by step. Based on the review of its chemical composition and pharmacological effects, combined with the definition of quality marker (Q-Marker), this study processed predictive analysis on Q-Marker of Cassiae Semen at aspects of plant affinity, component specificity, component availability, component measurability and the effects of processing on chemical composition and so on, which provides a scientific basis for quality evaluation of Cassiae Semen.