血清超敏 C反应蛋白与急性脑梗死的相关性研究

目的 探讨血清中超敏C反应蛋白(hsCRP)水平与急性脑梗死的相关性.方法 选取2019年10月至2020年3月安徽省第二人民医院收治的急性脑梗死病人50例作为观察组,收集同期于安徽省第二人民医院进行健康体检者50例作为健康对照组.检测两组hsCRP与血常规,比较两组hsCRP、白细胞(WBC)计数水平以及不同损伤程度急性脑梗死病人hsCRP水平.结果 观察组hsCRP、WBC血清计数水平高于健康对照组,差异有统计学意义(P<0.05);轻型急性脑梗死病人hsCRP水平为(5.12±2.34)mg/L,中型急性脑梗死病人hsCRP水平为(8.57±2.42)mg/L,重型急性脑梗死病人hsCRP水平为(11.64±3.68)mg/L.中型急性脑梗死病人hsCRP水平高于轻型,重型急性脑梗死病人hsCRP水平高于中型,均差异有统计学意义(P<0.05).结论 血清hsCRP可作为特异性血清学标志物用于急性脑梗死的病情评估,其与急性脑梗死的发生有密切相关性.

Correlation between serum hypersensitive c-reactive protein and acute cerebral infarction

Objective To investigate the correlation between serum hypersensitive c-reactive protein and acute cerebral infarction. Methods 50 cases of acute cerebral infarction patients admitted to neurology department of our hospital from October 2019 to March2020 were selected as the observation group. HsCRP and WBC count levels and hsCRP levels were compared between the two groups.Results hsCRP and WBC count in the observation group were much higher than the normal control group, the difference has significance, with statistical significance (P < 0.05). HsCRP level was (5.12± 2.34)mg/L for mild acute cerebral infarction patients, (8.57±2.42)mg/L for medium acute cerebral infarction patients, and (11.64±3.68)mg/L for severe acute cerebral infarction patients. HsCRPlevel of medium acute cerebral infarction patients was higher than that of light, and that of heavy acute cerebral infarction patients washigher than that of medium,with statistical significance (P < 0.05) .Conclusion Hypersensitive c-reactive protein can be used as anindicator of acute cerebral infarction, which is closely related to the occurrence of acute cerebral infarction.