| 肺癌手术前后血清STNER Ⅰ变化的临床意义 |
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| 引用本文： | 阮征,杨明训,等. 肺癌手术前后血清STNER Ⅰ变化的临床意义[J]. 浙江临床医学, 2001, 3(1): 8-9 |
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| 作者姓名： | 阮征 杨明训 等 |
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| 作者单位： | 浙江省桐乡市第二人民医院(阮征!314511,杨明训!314511,王剑云!314511,黄海龙!314511),上海市第一人民医院胸外科(王裕发!200080) |
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| 摘 要： | 目的 研究肺癌患者手术前后血清STNFR Ⅰ的变化。方法 采用ELISA方法测定了80例肺癌患者,14例非肿瘤患者,61例志愿成年人。结果 肺癌患者中STNFR Ⅰ的平均水平明显高于健康对照组和非肿瘤组（P＜0．01）。按肿瘤TNM分期,肺癌Ⅲ-Ⅳ期患者远高于Ⅰ－Ⅱ期升 高幅度,与疾病分期明显相关,而与病理类型无关（P＜0．01）。结论 排除自身免疫疾病和感染,STNFR Ⅰ的测定对肿瘤的诊断,筛选,预后有辅助意义。也可了解病人的异常免疫状态,为肿瘤患者的免疫治疗提供依据及观察指标。
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| 关 键 词： | 肺癌 STNFRⅠ 外科手术 治疗 |
The serum levels of STNFR |
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| . The serum levels of STNFR[J]. Zhejiang Clinical Medical Journal, 2001, 3(1): 8-9 |
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| Abstract: | Objective To detect the serum levels of STNFR I in lung cancer patients. Methods The serum STNFR I was measured by ELISA. 80 lung cancer patients, 14 non-tumor patients and 61 healthy volunteers were involved in our study. Results The serum STNFR I in lung cancer patients was higher significantly than healthy control group and non-tumor group (p<0.01). The levels of STNFR I varied with stages of cancer, but were irrelative with pathology of tumors. The serum levels of STNFR I in stage III-IV tumors was higher than that in stage I-II tumors (p<0.01). Conclusion Detection of serum STNFR I was of high value in the screening and diagnosis of lung cancer. It also helped to understand the abnormal immune states of patients, and provided a basis for immnotherapy. |
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| Keywords: | Lung cancer STNFR I |
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