| 宫环止血片对置铜宫内节育器家兔子宫匀浆中一氧化氮及一氧化氮合酶的影响 |
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| 引用本文： | 尤昭玲,付灵梅,雷磊,文乐兮. 宫环止血片对置铜宫内节育器家兔子宫匀浆中一氧化氮及一氧化氮合酶的影响[J]. 湖南中医药大学学报, 2001, 21(4): 12-14 |
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| 作者姓名： | 尤昭玲 付灵梅 雷磊 文乐兮 |
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| 作者单位： | 湖南中医学院, |
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| 基金项目： | 湖南中医学院和深圳亿胜医药科技发展有限公司联合开发课题 |
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| 摘 要： | 探讨宫环止血片治疗铜宫内节育器（Cu-IUD）所致子宫异常出血的作用机理。用吲美辛作对照，观察了宫环止血对置Cu－IUD家兔子宫匀浆液中一氧化氮（NO）含量及一氧化氮合酶（NOS）活力的影响。结果显示：宫环止血片能降低置Cu－IUD家兔子宫局部的NO的含量及NOS的活力，从而影响子宫螺旋动脉的舒缩功能，减少出血。提示宫环止血片对置Cu－IUD引起的出血有良好的防治作用。
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| 关 键 词： | 宫环止血片 宫内避孕器 铜 子宫出血 一氧化氮 一氧化氮合酶 中药 动物实验 |
| 文章编号： | 1000-5633(2001)04-0012-03 |
| 修稿时间： | 2001-09-26 |
Experimental Research on the Effects of Gonghuanzhixue Pian on the Content of NO and Activity of NOS in Uterine Tissue of Rabbits Wearing Cu-IUD |
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| You Zhaoling,Fu Lingmei,Lei Lei,et al. Experimental Research on the Effects of Gonghuanzhixue Pian on the Content of NO and Activity of NOS in Uterine Tissue of Rabbits Wearing Cu-IUD[J]. Journal of Traditional Chinese Medicine University of Hunan, 2001, 21(4): 12-14 |
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| Authors: | You Zhaoling Fu Lingmei Lei Lei et al |
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| Abstract: | The aim is to explore the mechanism of Gonghuanzhixue Pian treating endometrorrhagia caused by Cu-IUD. In constrast with indomethacin, we investigated the effects of Gonghuanzhixue Pian on the content of NO and activity of the NOS in uterine tissues of Cu-IUD-wearing rabbits. The results show that Gonghuanzhixue Pian can decrease the content of NO and activity of NOS and influence the constrictive function of the spirartery in the uterine of rabbits wearing Cu-IUD The results suggest that endometrorrhagia caused by CuIUD-wearing can be prevented and cured effectively with Gonghuanzhixue Pian. |
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| Keywords: | Gonghuanzhixue Pian intrauterine device.copper (CuIUD) endometrorrhagia nitrous oxide(NO) nitrous oxide synthetase(NOS) Soothing liver activating blood cyperas rtundus. |
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